Tissue repair & recovery researchPreclinical (animal) evidence

BPC-157 (PS-201)

A research guide to BPC-157: what the published literature covers, how it is characterized, and how to reconstitute, store, and verify it. Written as research framing, never usage guidance.

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Overview

Compounds in this area appear in the tissue-repair and recovery literature, often studied for angiogenesis, cytoprotection, and cell-migration signaling. The evidence base is predominantly preclinical, so this guide labels the study type for every cited claim and never reads animal or in-vitro data as human efficacy.

A synthetic pentadecapeptide derived from a gastric protein, one of the most-studied compounds in preclinical tissue-repair research.

Evidence at a glance: Preclinical (animal) evidence

The cited evidence here is preclinical animal-model work, with limited or no human-trial data. Read the research profile accordingly.

Molecular identity

Molecular formula
C62H98N16O22
Molecular weight
1419.5 g/mol
CAS number
137525-51-0
Amino acids
15
Appearance
White lyophilized powder
Purity (HPLC)
99.3%

Researched mechanism

Studied for pro-angiogenic and cytoprotective signaling (VEGFR2/eNOS pathways) in a wide range of tissue models.

Described as a mechanism characterized in the literature, not an effect you should expect from use.

What the published research shows

  • Accelerated tendon-to-bone and soft-tissue healing in rodent models.

    animal modelrat tendon/muscle models·Chang et al., 2011 (representative)PubMed ↑
  • Gastrointestinal protective effects widely characterized preclinically.

    animal modelrodent GI models·Sikiric et al. (representative)PubMed ↑

Honest note on evidence: The literature is almost entirely preclinical (animal/in vitro). Human trial data is limited.

Every citation states its study type and population, so preclinical data is never presented as human-efficacy evidence.

How it compares

VersusAttributeNote
TB-500MechanismOften co-studied for recovery; TB-500 acts via actin/Tβ4 pathways.
KPVFocusKPV is studied more for anti-inflammatory signaling.

Reconstitution

Concentration math only: adding bacteriostatic water to the vial gives the resulting mg/mL shown below. This is not usage guidance.

VialBacteriostatic waterConcentration
5 mg2 mL2.5 mg/mL
10 mg2 mL5 mg/mL
Open the reconstitution calculator →

Storage & stability

StateTemperatureDuration
Lyophilized (unopened)-20°C24 months
Reconstituted2–8°Cup to 4 weeks

Common questions

Is BPC-157 well studied in humans?+

No. The published literature is overwhelmingly preclinical. We state that in the evidence section rather than imply human efficacy.

What is it commonly paired with in research?+

TB-500 in recovery-research protocols; see the related stacks.

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