Overview
Longevity and cellular-research compounds are studied for pathways such as mitochondrial signaling, telomere biology, and redox balance, mostly in preclinical work. Some rest on a limited, single-group literature. Where that is the case, this guide says so rather than overstating it.
An essential cellular coenzyme central to energy metabolism and studied extensively in aging and mitochondrial research.
Evidence at a glance: Mechanistic / in-vitro only
The published record here is mechanistic or in-vitro only. No human-efficacy conclusion can be drawn from it.
Molecular identity
- Molecular formula
- C21H27N7O14P2
- Molecular weight
- 663.43 g/mol
- CAS number
- 53-84-9
- Appearance
- White to off-white powder
- Purity (HPLC)
- 99.4%
Researched mechanism
Serves as a redox coenzyme and substrate for sirtuins and PARPs; studied for mitochondrial and cellular-stress pathways.
Described as a mechanism characterized in the literature, not an effect you should expect from use.
What the published research shows
Central role in NAD+ metabolism and sirtuin activity characterized broadly.
Every citation states its study type and population, so preclinical data is never presented as human-efficacy evidence.
How it compares
| Versus | Attribute | Note |
|---|---|---|
| 5-Amino-1MQ | Pathway | Both intersect NAD+ biology from different angles. |
Reconstitution
Concentration math only: adding bacteriostatic water to the vial gives the resulting mg/mL shown below. This is not usage guidance.
| Vial | Bacteriostatic water | Concentration |
|---|---|---|
| 500 mg | 5 mL | 100 mg/mL |
| 1000 mg | 10 mL | 100 mg/mL |
Storage & stability
| State | Temperature | Duration |
|---|---|---|
| Lyophilized (unopened) | -20°C | 24 months |
| Reconstituted | 2–8°C | up to 1 week |
Common questions
Why the short reconstituted window?+
NAD+ is less stable in solution; use promptly and keep refrigerated (see storage table).
