Metabolic researchIncludes human-trial data

Semaglutide (PS-103)

A research guide to Semaglutide: what the published literature covers, how it is characterized, and how to reconstitute, store, and verify it. Written as research framing, never usage guidance.

3 min read·For Research Use Only·View product, from $67.01→

Overview

Most metabolic-research compounds in this catalog are incretin-system agonists (GLP-1, GIP, and glucagon-receptor ligands) and related signaling molecules. The published literature studies them for metabolic and body-composition research endpoints. This guide describes how the compound is characterized and what that research covers. It is not usage guidance and makes no claim about outcomes from use.

A long-acting GLP-1 receptor agonist and one of the most-referenced peptides in modern metabolic research.

Evidence at a glance: Includes human-trial data

The cited record for this compound includes human-trial data. Each claim below still states its study type and population, so the scope of that evidence stays explicit.

Molecular identity

Molecular formula
C187H291N45O59
Molecular weight
4113.6 g/mol
CAS number
910463-68-2
Amino acids
31
Appearance
White to off-white lyophilized powder
Purity (HPLC)
99.3%

Researched mechanism

Selective GLP-1 receptor agonism with a fatty-acid modification conferring a long half-life via albumin binding.

Described as a mechanism characterized in the literature, not an effect you should expect from use.

What the published research shows

  • Extensive phase 3 evidence across glycemic and weight endpoints.

    human trialadults, multiple RCTs·STEP / SUSTAIN programs (representative)PubMed ↑

Every citation states its study type and population, so preclinical data is never presented as human-efficacy evidence.

How it compares

VersusAttributeNote
TirzepatideReceptor targetsTirzepatide adds GIP; semaglutide is GLP-1 only.
CagrilintideClassCagrilintide is an amylin analog, often studied alongside GLP-1 agonists.

Reconstitution

Concentration math only: adding bacteriostatic water to the vial gives the resulting mg/mL shown below. This is not usage guidance.

VialBacteriostatic waterConcentration
10 mg2 mL5 mg/mL
20 mg2 mL10 mg/mL
Open the reconstitution calculator →

Storage & stability

StateTemperatureDuration
Lyophilized (unopened)-20°C24 months
Reconstituted2–8°Cup to 4 weeks

Common questions

How should it be stored after mixing?+

Refrigerated at 2–8°C and used within the storage window shown in the table above.

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