Cognitive / neuro researchPreclinical (animal) evidence

Semax (PS-301)

A research guide to Semax: what the published literature covers, how it is characterized, and how to reconstitute, store, and verify it. Written as research framing, never usage guidance.

3 min read·For Research Use Only·View product, from $77.00→

Overview

The cognitive and neuro-research peptides here are studied for neurotrophic and neuromodulatory signaling, largely in preclinical and early clinical literature. Evidence depth varies widely across the group, so this guide states the strength of the published record for each compound plainly rather than implying a uniform effect.

A synthetic peptide derived from ACTH(4-10), studied for neuroprotective and BDNF-related signaling.

Evidence at a glance: Preclinical (animal) evidence

The cited evidence here is preclinical animal-model work, with limited or no human-trial data. Read the research profile accordingly.

Molecular identity

Molecular formula
C37H51N9O10S
Molecular weight
813.9 g/mol
CAS number
80714-61-0
Amino acids
7
Appearance
White lyophilized powder
Purity (HPLC)
99%

Researched mechanism

Studied for modulation of BDNF/TrkB signaling and neuroprotection in CNS models.

Described as a mechanism characterized in the literature, not an effect you should expect from use.

What the published research shows

  • BDNF modulation and neuroprotective effects in preclinical work.

    animal modelrodent CNS models·representative Semax literaturePubMed ↑

Honest note on evidence: Most published work originates from a small set of research groups; evidence is largely preclinical.

Every citation states its study type and population, so preclinical data is never presented as human-efficacy evidence.

How it compares

VersusAttributeNote
SelankFocusSelank is studied more for anxiolytic-type signaling; Semax for neurotrophic.

Reconstitution

Concentration math only: adding bacteriostatic water to the vial gives the resulting mg/mL shown below. This is not usage guidance.

VialBacteriostatic waterConcentration
10 mg1 mL10 mg/mL
Open the reconstitution calculator →

Storage & stability

StateTemperatureDuration
Lyophilized (unopened)-20°C24 months
Reconstituted2–8°Cup to 4 weeks

Common questions

Is Semax paired with Selank?+

Research protocols sometimes study them together; see the cognitive stack.

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