Overview
The cognitive and neuro-research peptides here are studied for neurotrophic and neuromodulatory signaling, largely in preclinical and early clinical literature. Evidence depth varies widely across the group, so this guide states the strength of the published record for each compound plainly rather than implying a uniform effect.
A synthetic peptide derived from ACTH(4-10), studied for neuroprotective and BDNF-related signaling.
Evidence at a glance: Preclinical (animal) evidence
The cited evidence here is preclinical animal-model work, with limited or no human-trial data. Read the research profile accordingly.
Molecular identity
- Molecular formula
- C37H51N9O10S
- Molecular weight
- 813.9 g/mol
- CAS number
- 80714-61-0
- Amino acids
- 7
- Appearance
- White lyophilized powder
- Purity (HPLC)
- 99%
Researched mechanism
Studied for modulation of BDNF/TrkB signaling and neuroprotection in CNS models.
Described as a mechanism characterized in the literature, not an effect you should expect from use.
What the published research shows
BDNF modulation and neuroprotective effects in preclinical work.
Honest note on evidence: Most published work originates from a small set of research groups; evidence is largely preclinical.
Every citation states its study type and population, so preclinical data is never presented as human-efficacy evidence.
How it compares
| Versus | Attribute | Note |
|---|---|---|
| Selank | Focus | Selank is studied more for anxiolytic-type signaling; Semax for neurotrophic. |
Reconstitution
Concentration math only: adding bacteriostatic water to the vial gives the resulting mg/mL shown below. This is not usage guidance.
| Vial | Bacteriostatic water | Concentration |
|---|---|---|
| 10 mg | 1 mL | 10 mg/mL |
Storage & stability
| State | Temperature | Duration |
|---|---|---|
| Lyophilized (unopened) | -20°C | 24 months |
| Reconstituted | 2–8°C | up to 4 weeks |
Common questions
Is Semax paired with Selank?+
Research protocols sometimes study them together; see the cognitive stack.



