Tissue repair & recovery researchPreclinical (animal) evidence

TB-500 (PS-202)

A research guide to TB-500: what the published literature covers, how it is characterized, and how to reconstitute, store, and verify it. Written as research framing, never usage guidance.

3 min read·For Research Use Only·View product, from $53.21→

Overview

Compounds in this area appear in the tissue-repair and recovery literature, often studied for angiogenesis, cytoprotection, and cell-migration signaling. The evidence base is predominantly preclinical, so this guide labels the study type for every cited claim and never reads animal or in-vitro data as human efficacy.

A synthetic version of the active region of Thymosin β4, studied for actin regulation, angiogenesis, and tissue repair.

Evidence at a glance: Preclinical (animal) evidence

The cited evidence here is preclinical animal-model work, with limited or no human-trial data. Read the research profile accordingly.

Molecular identity

Molecular formula
C212H350N56O78S
Molecular weight
4963.4 g/mol (Tβ4)
CAS number
885340-08-9
Amino acids
43
Appearance
White lyophilized powder
Purity (HPLC)
99.1%

Researched mechanism

Regulates actin polymerization; studied for cell migration, angiogenesis, and wound repair.

Described as a mechanism characterized in the literature, not an effect you should expect from use.

What the published research shows

  • Promoted cell migration and repair in preclinical tissue models.

    animal modelrodent cardiac/dermal models·Goldstein et al. (representative)PubMed ↑

Honest note on evidence: Evidence is largely preclinical.

Every citation states its study type and population, so preclinical data is never presented as human-efficacy evidence.

How it compares

VersusAttributeNote
BPC-157MechanismDifferent pathway; commonly co-studied for recovery.

Reconstitution

Concentration math only: adding bacteriostatic water to the vial gives the resulting mg/mL shown below. This is not usage guidance.

VialBacteriostatic waterConcentration
5 mg2 mL2.5 mg/mL
10 mg2 mL5 mg/mL
Open the reconstitution calculator →

Storage & stability

StateTemperatureDuration
Lyophilized (unopened)-20°C24 months
Reconstituted2–8°Cup to 4 weeks

Common questions

Is TB-500 the same as Thymosin β4?+

TB-500 refers to the active fragment; full-length Thymosin β4 is the parent protein. Sequences differ.

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