Overview
Compounds in this area appear in the tissue-repair and recovery literature, often studied for angiogenesis, cytoprotection, and cell-migration signaling. The evidence base is predominantly preclinical, so this guide labels the study type for every cited claim and never reads animal or in-vitro data as human efficacy.
A synthetic version of the active region of Thymosin β4, studied for actin regulation, angiogenesis, and tissue repair.
Evidence at a glance: Preclinical (animal) evidence
The cited evidence here is preclinical animal-model work, with limited or no human-trial data. Read the research profile accordingly.
Molecular identity
- Molecular formula
- C212H350N56O78S
- Molecular weight
- 4963.4 g/mol (Tβ4)
- CAS number
- 885340-08-9
- Amino acids
- 43
- Appearance
- White lyophilized powder
- Purity (HPLC)
- 99.1%
Researched mechanism
Regulates actin polymerization; studied for cell migration, angiogenesis, and wound repair.
Described as a mechanism characterized in the literature, not an effect you should expect from use.
What the published research shows
Promoted cell migration and repair in preclinical tissue models.
Honest note on evidence: Evidence is largely preclinical.
Every citation states its study type and population, so preclinical data is never presented as human-efficacy evidence.
How it compares
| Versus | Attribute | Note |
|---|---|---|
| BPC-157 | Mechanism | Different pathway; commonly co-studied for recovery. |
Reconstitution
Concentration math only: adding bacteriostatic water to the vial gives the resulting mg/mL shown below. This is not usage guidance.
| Vial | Bacteriostatic water | Concentration |
|---|---|---|
| 5 mg | 2 mL | 2.5 mg/mL |
| 10 mg | 2 mL | 5 mg/mL |
Storage & stability
| State | Temperature | Duration |
|---|---|---|
| Lyophilized (unopened) | -20°C | 24 months |
| Reconstituted | 2–8°C | up to 4 weeks |
Common questions
Is TB-500 the same as Thymosin β4?+
TB-500 refers to the active fragment; full-length Thymosin β4 is the parent protein. Sequences differ.



