Metabolic researchIncludes human-trial data

Tesamorelin (PS-110)

A research guide to Tesamorelin: what the published literature covers, how it is characterized, and how to reconstitute, store, and verify it. Written as research framing, never usage guidance.

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Overview

Most metabolic-research compounds in this catalog are incretin-system agonists (GLP-1, GIP, and glucagon-receptor ligands) and related signaling molecules. The published literature studies them for metabolic and body-composition research endpoints. This guide describes how the compound is characterized and what that research covers. It is not usage guidance and makes no claim about outcomes from use.

A growth-hormone-releasing hormone (GHRH) analog studied for effects on GH/IGF-1 axis and visceral adipose tissue.

Evidence at a glance: Includes human-trial data

The cited record for this compound includes human-trial data. Each claim below still states its study type and population, so the scope of that evidence stays explicit.

Molecular identity

Molecular formula
C221H366N72O67S
Molecular weight
5135.9 g/mol
CAS number
218949-48-5
Amino acids
44
Appearance
White lyophilized powder
Purity (HPLC)
99%

Researched mechanism

GHRH receptor agonism stimulating endogenous GH release; studied for visceral-fat endpoints.

Described as a mechanism characterized in the literature, not an effect you should expect from use.

What the published research shows

  • Studied for change in visceral adipose tissue in controlled human trials.

    human trialadults, phase 3 RCTs·Falutz et al., 2010 (representative)PubMed ↑

Every citation states its study type and population, so preclinical data is never presented as human-efficacy evidence.

How it compares

VersusAttributeNote
SermorelinStabilityTesamorelin is a stabilized GHRH analog with a longer profile.
CJC-1295ClassBoth influence the GH axis via GHRH-related mechanisms.

Reconstitution

Concentration math only: adding bacteriostatic water to the vial gives the resulting mg/mL shown below. This is not usage guidance.

VialBacteriostatic waterConcentration
10 mg2 mL5 mg/mL
Open the reconstitution calculator →

Storage & stability

StateTemperatureDuration
Lyophilized (unopened)-20°C24 months
Reconstituted2–8°Cup to 2 weeks

Common questions

How long is it stable once mixed?+

GHRH analogs are less stable in solution; use within ~2 weeks refrigerated (see storage table).

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