Tissue repair & recovery researchPreclinical (animal) evidence

Thymosin Beta-4 (PS-203)

A research guide to Thymosin Beta-4: what the published literature covers, how it is characterized, and how to reconstitute, store, and verify it. Written as research framing, never usage guidance.

3 min read·For Research Use Only·View product, from $60.00→

Overview

Compounds in this area appear in the tissue-repair and recovery literature, often studied for angiogenesis, cytoprotection, and cell-migration signaling. The evidence base is predominantly preclinical, so this guide labels the study type for every cited claim and never reads animal or in-vitro data as human efficacy.

The full-length 43-amino-acid Thymosin β4 peptide, studied for actin regulation and regenerative signaling.

Evidence at a glance: Preclinical (animal) evidence

The cited evidence here is preclinical animal-model work, with limited or no human-trial data. Read the research profile accordingly.

Molecular identity

Molecular formula
C212H350N56O78S
Molecular weight
4963.4 g/mol
CAS number
77591-33-4
Amino acids
43
Appearance
White lyophilized powder
Purity (HPLC)
98.9%

Researched mechanism

Sequesters G-actin and modulates cell migration, angiogenesis, and inflammation in research models.

Described as a mechanism characterized in the literature, not an effect you should expect from use.

What the published research shows

  • Regenerative and anti-inflammatory effects in preclinical models.

    animal modelrodent injury models·representative Tβ4 literaturePubMed ↑

Honest note on evidence: Evidence is largely preclinical.

Every citation states its study type and population, so preclinical data is never presented as human-efficacy evidence.

How it compares

VersusAttributeNote
TB-500LengthTB-500 is the active fragment; this is the full-length peptide.

Reconstitution

Concentration math only: adding bacteriostatic water to the vial gives the resulting mg/mL shown below. This is not usage guidance.

VialBacteriostatic waterConcentration
5 mg2 mL2.5 mg/mL
10 mg2 mL5 mg/mL
Open the reconstitution calculator →

Storage & stability

StateTemperatureDuration
Lyophilized (unopened)-20°C24 months
Reconstituted2–8°Cup to 4 weeks

Common questions

Full-length vs TB-500?+

This is the complete 43-aa peptide; TB-500 is the active region. See the comparison note.

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