Overview
Compounds in this area appear in the tissue-repair and recovery literature, often studied for angiogenesis, cytoprotection, and cell-migration signaling. The evidence base is predominantly preclinical, so this guide labels the study type for every cited claim and never reads animal or in-vitro data as human efficacy.
The full-length 43-amino-acid Thymosin β4 peptide, studied for actin regulation and regenerative signaling.
Evidence at a glance: Preclinical (animal) evidence
The cited evidence here is preclinical animal-model work, with limited or no human-trial data. Read the research profile accordingly.
Molecular identity
- Molecular formula
- C212H350N56O78S
- Molecular weight
- 4963.4 g/mol
- CAS number
- 77591-33-4
- Amino acids
- 43
- Appearance
- White lyophilized powder
- Purity (HPLC)
- 98.9%
Researched mechanism
Sequesters G-actin and modulates cell migration, angiogenesis, and inflammation in research models.
Described as a mechanism characterized in the literature, not an effect you should expect from use.
What the published research shows
Regenerative and anti-inflammatory effects in preclinical models.
Honest note on evidence: Evidence is largely preclinical.
Every citation states its study type and population, so preclinical data is never presented as human-efficacy evidence.
How it compares
| Versus | Attribute | Note |
|---|---|---|
| TB-500 | Length | TB-500 is the active fragment; this is the full-length peptide. |
Reconstitution
Concentration math only: adding bacteriostatic water to the vial gives the resulting mg/mL shown below. This is not usage guidance.
| Vial | Bacteriostatic water | Concentration |
|---|---|---|
| 5 mg | 2 mL | 2.5 mg/mL |
| 10 mg | 2 mL | 5 mg/mL |
Storage & stability
| State | Temperature | Duration |
|---|---|---|
| Lyophilized (unopened) | -20°C | 24 months |
| Reconstituted | 2–8°C | up to 4 weeks |
Common questions
Full-length vs TB-500?+
This is the complete 43-aa peptide; TB-500 is the active region. See the comparison note.



