Overview
Most metabolic-research compounds in this catalog are incretin-system agonists (GLP-1, GIP, and glucagon-receptor ligands) and related signaling molecules. The published literature studies them for metabolic and body-composition research endpoints. This guide describes how the compound is characterized and what that research covers. It is not usage guidance and makes no claim about outcomes from use.
A dual incretin agonist with a large published clinical literature across metabolic and glycemic endpoints. A benchmark reference compound in the category.
Evidence at a glance: Includes human-trial data
The cited record for this compound includes human-trial data. Each claim below still states its study type and population, so the scope of that evidence stays explicit.
Molecular identity
- Molecular formula
- C225H348N48O68
- Molecular weight
- 4813.5 g/mol
- CAS number
- 2023788-19-2
- Amino acids
- 39
- Appearance
- White lyophilized powder
- Purity (HPLC)
- 99.4%
Researched mechanism
Co-agonism at GIP and GLP-1 receptors; the GIP component is the main pharmacological differentiator from GLP-1-only agonists.
Described as a mechanism characterized in the literature, not an effect you should expect from use.
What the published research shows
Large phase 3 program characterized glycemic and body-weight endpoints.
Every citation states its study type and population, so preclinical data is never presented as human-efficacy evidence.
How it compares
| Versus | Attribute | Note |
|---|---|---|
| Semaglutide | Receptor targets | Tirzepatide adds GIP agonism; semaglutide is GLP-1 only. |
| Retatrutide | Receptor targets | Retatrutide adds a third (glucagon) receptor. |
Reconstitution
Concentration math only: adding bacteriostatic water to the vial gives the resulting mg/mL shown below. This is not usage guidance.
| Vial | Bacteriostatic water | Concentration |
|---|---|---|
| 10 mg | 1 mL | 10 mg/mL |
| 15 mg | 1 mL | 15 mg/mL |
| 20 mg | 1 mL | 20 mg/mL |
| 30 mg | 1 mL | 30 mg/mL |
| 60 mg | 2 mL | 30 mg/mL |
Storage & stability
| State | Temperature | Duration |
|---|---|---|
| Lyophilized (unopened) | -20°C | 24 months |
| Reconstituted | 2–8°C | up to 4 weeks |
Common questions
Is a larger vial more economical?+
Yes. The 60 mg vial has the lowest per-mg price. The price ladder is shown inline above.



